Skip Global navigation and goto content

It's a New Day in Public Health.

The Florida Department of Health works to protect, promote & improve the health of all people in Florida through integrated state, county & community efforts.

Skip MegaMenu and goto content

U=U (Undetectable=Untransmittable)

Contact Us

  •  850-595-6500 x1510

    Mailing Address

    Fairfield Service Center, 1295 West Fairfield Drive, Pensacola, Florida 32501 




Couple hugging on couch smiling at camera.

People living with HIV who take antiretroviral medication as prescribed and achieve and maintain an undetectable viral load cannot transmit HIV to their sexual partners.

Treatment with antiretroviral medication is recommended for all people living with HIV. The medication reduces the amount of HIV within the body and reduces the chance of transmission. That means healthier, longer lives.

Undetectable=Untransmittable, or U=U, is a powerful HIV prevention tool. It redefines living with HIV, reducing stigma and empowering people to live their lives to the fullest.

U=U Facts 

  • Undetectable means that a person living with HIV has such a small amount of virus in their blood it cannot be detected by a lab test.

  • Achieving an undetectable viral load is only the start. Staying undetectable is key for long-term health and prevention benefits.

Pregnant woman sitting on couch smiling at camera.

The Science 

  • U=U is based on studies that included more than 1,600 couples* and reported no sexual transmission.

  • So far, U=U has only been proven for sexual transmission. Other modes of transmission, like breastfeeding or injection-drug use, have not been fully studied.
  • Although U=U does not apply to breastfeeding, it is well known that, based on peer-reviewed studies conducted by the Journal of the American Medical Association and backed by the Centers for Disease Control and Prevention, pregnant women who are HIV positive and undetectable have an over 99% chance of NOT transmitting HIV while the baby is in utero and during delivery.

Male couple hugging and looking at camera.

*A clinical trial that included additional participants but also studied othe treatment factors. For more information on the science behind U=U, see thr Center for Disease Control and Preventions.
*Evidence of HOV Treatment and Viral Supression in Preventing the Sexual Transmission of HIV factsheet at


Other Prevention Facts 

  • People who are HIV negative can take pre-exposure prophylaxis (PrEP) to prevent acquiring HIV.

  • Condoms are still important for protecting against sexually transmitted infections and unintended pregnancy.

Young mom carrying child piggyback in park.

Here For U for assistance with medication, housing, and more. for info on HIV testing and healthy living.

Florida HIV/AIDS Hotline

  • 1-800-FLA-AIDS English
  • 1-800-545-SIDA Spanish
  • 1-800-AIDS-101 Hatian Creole
  • 1-888-503-7118 Hearing /Speech Impaired